Posts Tagged ‘Case Study’
Application of 3D Elekta VolumeViewTM image guided radiation therapy (IGRT) in treatment of locally advanced nasopharyngeal carcinoma – Tuen Mun Hospital, Hong Kong

Isodose Distribution
Patient history
A 34-year-old man was diagnosed to have a stage IVA (T4 N2 M0) NPC (nasopharyngeal carcinoma). Medical imaging showed a large tumor mass in the nasopharyngeal region with extensive involvement of neighboring structures including base of skull, sphenoid sinus, ethmoid sinuses and pituitary fossa. Multiple enlarged lymph nodes in both cervical regions were also reported.
Planned treatment

Depatrment of Clinical Oncology TMH
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MRI showing massive tumor with extensive involvement - CT scan showing skull base destruction
Read more about VolumeView here
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Potential of volumetric modulated arc therapy (VMAT) for anal cancer –
Anal cancer is primarily treated with radio chemotherapy and represents a complex treatment situation due to the size, shape and position of the pelvic planning treatment volume (PTV). Pelvic radiation therapy may cause significant acute and late toxicity, therefore advanced 3D treatment planning strategies as well as intensity modulated radiotherapy (IMRT) are used to reduce exposure to organs at risk (OAR). Volumetric modulated arc therapy (VMAT) may provide excellent dose distributions with very short treatment times. This case-based planning study explores this potential.
read more about VMAT for Anal Cancer

Re-treatment of a recurrent brain tumor using Elekta Synergy® S
Institution: Temple University Hospital, Philadelphia, USA
Patient: 63-year-old male
Diagnosis: NSCLC
Plan: Nine-field IMRT/SRT
Image guidance: VolumeView™ on-line
Treatment: Target – 1200cGy – single fraction
Patient diagnosis and history
A 63-year-old man with a six-month history of weight loss underwent a chest X-ray which revealed a right upper lobe mass. The patient later had a generalized seizure and was admitted to a local hospital, after which he had an MRI scan which revealed three metastatic lesions.
A CT scan of the chest revealed a 9cm right upper lobe mass with hilar and mediastinal lymphadenopathy. The patient had a fine needle aspirate biopsy of the right upper lobe mass that was compatible with non-small cell carcinoma of the lung (NSCCL). A bone scan revealed increased activity in the T6 vertebral body and the right intertrochanteric area of the right femur.
Previous radiation therapy
The patient had previously received whole brain irradiation, a total dose of 3500cGy was delivered in 14 fractions through parallel-opposed lateral fields.
Treatment
A step-and-shoot IMRT/stereotactic radiation therapy (SRT) plan (figure 1) for simultaneous treatment of multiple brain metastases (two cerebellar and a right temporal). Treatment planning was carried out using Philips Pinnacle®3 IMRT/SRT techniques. The patient was immobilized in a reinforced AcQuaPlast head mask. No sedation was employed.
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Axial dose distribution & Sagittal dose distribution
Deliver a higher dose to the prostate while sparing or minimizing the dose to the rectum, in an effort to reduce or eliminate acute and delayed rectal morbidity. Total session time, including patient positioning, ultrasound-guided targeting, and intensity modulated radiotherapy (IMRT) delivery should not exceed 30 minutes, maintaining the existing patient load. Rationale for IMRT approach Radiotherapy planning with PrecisePLAN® IMRT at United Radiation Oncology (URO) demonstrates a considerable decrease in radiation dose to the rectum.
Patient selection
Patients diagnosed with prostate cancer and referred to URO receive an initial consultation,consisting of history, physical exam, psychosocial assessment and discussion of treatment options. Candidates for IMRT are those patients with adverse prognostic factors, whose outcome may improve in response to dose escalation.Adequate localization of the prostate via ultrasound is critical, therefore the patient must be able to drink sufficient fluid to fill the bladder.
Read more on this Prostate Cancer Case Study
