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Posts Tagged ‘Brain Metastases’

Because of its minimal invasiveness, safety and effectiveness, Gamma Knife® surgery is increasingly used instead of, or in combination with, whole brain radiation therapy (WBRT) to treat patients with multiple brain metastases. In a recent clinical study, UPMC researchers assessed clinical outcomes and identified prognostic factors for and intracranial disease control among patients with 10 or more brain metastases treated on Leksell Gamma Knife Perfexion over a two-year period. Read the rest of this entry »
At the 2011 American Association of Neurological Surgeons (AANS) Annual Meeting, April 9-13 at the Colorado Convention Center, Elekta (booth #1717) will highlight characteristics of Leksell Gamma Knife® Perfexion™ that separate the system from other radiosurgery solutions. These include its dedication to intracranial cases, complete solution integration, industry-leading accuracy, “shrink-wrap” dose conformity and extensively proven clinical efficacy. Demonstrations of the system will emphasize that Perfexion is designed to minimize the risk of human error and radiation toxicity, while optimizing accuracy and dose conformance. Read the rest of this entry »
The volume of normal brain tissue exposed to radiation during treatment for multiple metastases appears to depend on which stereotactic radiosurgery system is employed, according to a recent study in the Journal of Neurosurgery. Comparing treatment plans developed for use by three different treatment systems for a single patient (already previously treated with Leksell Gamma Knife®), researchers found that Gamma Knife plans would result in “much smaller normal brain volumes receiving any particular dose” than the two other systems’ plans. Read the rest of this entry »
Among the most common sites for cancers to metastasize is the brain. According to the American Cancer Society, 20-40 percent of all cancer patients develop metastatic tumors in the brain. This is the single most common type of intracranial tumor. In the U.S. alone, around 150,000 people are diagnosed with brain metastases each year. The incidence continues to increase as advances are made in the treatment of systemic cancer. The most common primary sources of brain metastases are lung (17%), renal cell (10.5%), and breast (5.2%) cancer and melanoma (8%). Read the rest of this entry »
Gamma Knife® surgery sometimes referred to as stereotactic radiosurgery (SRS), is a non-invasive method for treating brain disorders. It is the delivery of a single, high dose of irradiation to a small and critically located intra-cranial volume through the intact skull. It is preferred for its extreme accuracy, efficiency and outstanding therapeutic response. Read the rest of this entry »
Wednesday, December 22, Good Morning America featured a segment on San Francisco Opera mezzo-soprano Zheng Cao and her successful treatment with Elekta's Leksell Gamma Knife® Perfexion™ radiosurgery system. Read the rest of this entry »

Photo courtesy of Dr. Jean Régis, Timone University Hospital, Marseilles, France

Photo courtesy of Dr. Jean Régis, Timone University Hospital, Marseilles, France

The refinements in Elekta’s Gamma Knife® surgery technology that created the fifth generation Leksell Gamma Knife® Perfexion™ are changing the approach to treating brain metastases and other brain disorders. With Perfexion, clinicians are applying therapy to multiple metastases in a single session, treating more non-malignant targets located in critical areas and planning increasingly tailored plans to meet individual patient needs. The result has been an upsurge in Perfexion sales and upgrades in North America.

Elekta recently announced its fourth quarter orders for Leksell Gamma Knife Perfexion, including Methodist Hospital (San Antonio), Memorial Hermann-Texas Medical Center (Houston), NewYork-Presbyterian Hospital and Swedish Cancer Institute (Seattle).

“Since the introduction of Perfexion, 40 percent of Gamma Knife systems in North America are, or will soon be, Perfexion systems,” says Thomas McKay, Senior Marketing Manager for Elekta Neuroscience <http://www.elekta.com/neuroscience> . “The benchmark upon which all other radiosurgery systems are measured, the capabilities of Perfexion continue to evolve, fusing the skills of the clinician with the science of radiosurgery.”

Read more at: http://www.elekta.com/healthcare_international_press_release_20071054.php.

First in the Southeast and fourth in the nation to host Leksell Gamma Knife®, Piedmont Hospital recently celebrated its 20th anniversary.

To mark the occasion, a reception was held at the hospital on Wednesday, September 23, honoring the 2,290 patients with malignant and non-malignant brain tumors and functional brain disorders who have received Gamma Knife surgery at the hospital’s Gamma Knife center. During the reception, an award was presented on behalf of Elekta to the staff of Piedmont Hospital by Senior Vice President of Elekta Neuroscience, Mark Symons.

Piedmonth Hospital Group

Piedmont Hospital Group

Five patients in particular were honored at the event, including Bill Reynolds of Lilburn, Shirley Blevins of Chattanooga, Kim Vining of Atlanta, Max Andrews of Dacula and Scott Calhoun of Atlanta. All heroes, their stories are below:

Bill Reynolds

Bill Reynolds

Bill Reynolds (trigeminal neuralgia)
Fifty-seven-year-old Bill Reynolds started to experience startling and excruciating pain shoot up the left side of his jaw any time he moved his mouth – to brush his teeth, to eat, to talk. It was a pain so intense he would almost black out. Diagnosed with trigeminal neuralgia, a painful chronic nerve disorder named for the three-part nerve that supplies sensations to all parts of the face, Reynolds found relief from prescription drugs. But through the years the pain started to break through. Piedmont neurologists presented Reynolds with several surgical options, but they agreed on the Gamma Knife surgery because it had the least risk and most potential for a positive outcome. Now, Reynolds can continue to do the job he is so passionate about – talking to various audiences all day as spokesperson for the National Parks Service.

Shirley Blevins

Shirley Blevins

Shirley Blevins (brain cancer)
Fourteen years ago, Shirley Blevins’ family noticed subtle cues that she was struggling with balance and memory. Then, a well-timed visit to the eye doctor revealed a brain tumor. A friend in Chattanooga told her about Gamma Knife surgery and convinced Blevins to travel to Atlanta to consult with Piedmont physicians. The day after Gamma Knife surgery Blevins says she was back to her old self again. Nearly a decade passed as she continued life as normal, making the suggested clinical follow up visits. Considering herself cured, she eventually stopped making the trip to Atlanta. Then, in the fall of 2007, her family started to notice the same worrisome symptoms. This time the MRI revealed a brain tumor the size of three golf balls – too large for Gamma Knife surgery. Several local physicians gave her similar dreaded news – they did not think she could survive neurosurgery. Not satisfied, she turned back to Atlanta where Piedmont neurosurgeons restored the family’s hope and confidence. Blevins survived the eight-and-a-half-hour craniotomy. Then, during a follow up visit, doctors saw a shadow on her brain MRI. A second Gamma Knife procedure quickly destroyed the cancerous cells. Today, at 70, she says she is physically and mentally stronger than ever.

Kim Vining

Kim Vining

Kim Vining (brain metastases)
No doubt about it, Kim Vining is a warrior. She has survived a nine-year battle with cancer that began when she was diagnosed with a rare, very aggressive breast cancer at age 37. Routine cancer treatment followed: chemotherapy, radiation and surgery. Less than two years later doctors found cancer in her lymph nodes and six lesions in her brain. Vining endured five weeks of daily whole-brain radiation, which killed both healthy and cancerous cells. Her brain was cancer-free again, but as the years passed Vining experienced warfare with another kind of breast cancer in addition to lung, back and hip cancers. Then, in 2007, cancer once again metastasized to different parts of her brain on two separate occasions. Both times, Gamma Knife surgery irradiated the lesions. Vining says of all of her various cancer treatments the brain cancer diagnosis was the scariest. “I thought, ‘This is it. I’m not going to survive this.’” But Gamma Knife surgery worked. “It was the easiest treatment of all.” Drug therapy is still a daily part of her routine to prevent cancer cells from reproducing, but the drug doesn’t cross the blood/brain barrier, so Vining lives every day knowing the cancer could settle back in her brain. “I keep working hard,” she says. “And in my spare time I read a lot and do crossword puzzles and Sudoku.” Brain exercises make Vining feel strong and ready to handle new challenges that may lie ahead.

Max Andrews

Max Andrews

Max Andrews (brain metastases)
Smaller than most other boys in grade school, Max Andrews learned survival strategies at an early age. But even a ninth degree black belt in karate couldn’t protect him from his first real health issue at age 60 – cancer. A dry, persistent cough was first diagnosed as pneumonia, but later, a pulmonologist told him it was cancer. A lung biopsy revealed even worse news: the cancer actually originated in his kidney and had already metastasized to his lung, adrenal glands and brain. Andrews had a craniotomy to surgically remove the brain cancer. Then, a few months later, an MRI revealed three more small lesions. He had a successful Gamma Knife procedure, and then six months later, another small brain lesion was found. Andrews faces on-going challenges because renal cell carcinoma can easily get into the bloodstream and go anywhere in the body. Every six weeks he has a brain MRI and a full-body CT scan. “I’ve gone through many treatments, including traditional brain surgery,” says Andrews. “The Gamma Knife was so different from everything else – I simply had the procedure, was up and walking in a few hours, and then was back to work the next day.”

Scott Calhoun

Scott Calhoun

Scott Calhoun (brain tumor)
Honeymooning in the Canadian Rockies, Scott Calhoun said goodnight to his bride and then did the same thing he did every night since he was 12 – he turned on the radio to fall asleep. Lucky for him, his new wife objected. The silence of the night drew attention to a whishing sound in his left ear. “It was not bothersome or painful, but I started to hear it every night,” Calhoun recalls. His primary care physician referred him to an ENT, where a CAT scan, brain MRI, and then biopsy revealed the source – a rare, benign tumor in Calhoun’s skull, just behind his eardrum. The tumor, called schwannoma, was partly embedded in his temporal bone and was starting to press against his brainstem. Calhoun first required a craniotomy to remove a large portion of the tumor. Then, after four weeks of recovery, the Gamma Knife targeted the remaining tumor cells with intense radiation and Calhoun was back at home the next day. That was nearly 20 years ago. Today, Calhoun is still tumor-free and sleeping soundly.

Gamma Knife Perfexion Sector Drive Motors

Gamma Knife Perfexion Sector Drive Motors

“We started out using radiosurgery for treating patients with single brain metastases, but treatments have evolved to the point where we are now routinely treating newly diagnosed brain metastasis in patients with up to three or four tumors,” Dr. Chang said.

“Cancer patients in general are surviving longer as more effective systemic treatments become available, but as survival increases, patients are also developing more brain metastases. To help those patients over the long term, we need to safely and efficiently treat brain metastases when they appear while preserving neurocognitive function and minimizing any damage to the brain. Radiosurgery is also chemo-friendly, allowing patients to return to their chemotherapy program with minimal delay.”

Read the entire Article by John LeBas here: http://www2.mdanderson.org/depts/oncolog/articles/09/7-8-julaug/7-8-09-1.html

Elekta offers the world’s most complete portfolio of stereotactic treatment solutions for the treatment of cancer and diseases of the brain, spine and body. The resulting systems’ design and performance reflect decades of leadership and innovation.

Our radiation oncology and neurosurgery customers face the constant cost-benefit challenge of wanting to adopt the most advanced treatment protocols within the constraints of the resources available. Elekta Axesse™ has been specifically developed to help meet this challenge, to bring the highest treatment quality to the maximum number of patients.

Resource management benefits

Caseload versatility • Workflow efficiency • Patient throughput

Treatment quality benefits

Patient safety • Targeting accuracy • Dose escalation • Hypofractionation

A wide range of stereotactic and intensity modulated treatments

Lung • Liver • Prostate • Head-and-neck • Spinal metastases • Large brain metastases