NeuroMag
Elekta and Orasi Medical have released a white paper detailing the opportunity for utilizing magnetoencephalography (MEG) technology to accelerate the development of drugs to treat neurological disorders. The paper describes MEG technology, its current clinical and research use, illustrates the comparison of MEG to EEG and importantly demonstrates how MEG can improve and accelerate the development of Central Nervous System (CNS) drugs.
The release of the paper comes at a critical time. With the average duration to bring a CNS drug to market exceeding 12 years—and only seven percent of neurological drugs making it to market—pharmaceutical companies are looking for technologies to assess the effect of drugs earlier and more accurately in the development process. “There is a critical need for better tools to ascertain brain function in drug development, as well as novel biomarkers that identify neurological drug and disease signatures,” said Michael Gold, Vice President, GlaxoSmithKline.
“We have heard firsthand from pharmaceutical thought leaders that there is no one modality that solves the current needs in CNS clinical drug development,” said Stephen Otto, Chairman of Elekta’s Neuromag Business. “The technical advantages and patient-friendly qualities of MEG make it a natural fit for the measurement of CNS drugs.”
To read more about how this novel application of MEG can accelerate drug development, reduce costs and improve CNS drug innovation by measuring neurological drug effects and real-time brain function throughout key phases of the drug development process, click here: www.orasimedical.com/2010megwhitepaper.
Click this link To learn more about the Elekta Neuromeg
Transcript from interview with Patricia Kuhl and Andrew Meltzoff from I–LABS highlighting MEG technology. (Marcie Sillman)
Do you remember those cartoons you watched as a kid? When Mickey Mouse or Huckleberry Hound got a great idea, we’d see a bulb light up over their heads. I’m Marcie Sillman. We hear a lot about the need to foster creative thinkers for the 21st century. That led me to wonder about the roots of creativity, and how it manifests in different ways for different people.
TRANSCRIPT
Sillman: A couple of years ago, I spoke to William Calvin about creativity. He’s a neurophysiologist who’s written extensively about how our brains work. Calvin believes creativity isn’t a rare talent reserved for extraordinary people.
Calvin: “To me, language is the everyday creative form we all have. We speak sentences we’ve never spoken before. We manage to take that idea; we manage to implant it in someone else’s head.”
Read the entire article here: http://www.kuow.org/program.php?id=20490
A new medical imaging lab in the Maritimes could detect and treat neurological diseases, disorders and injuries earlier by recording the brain in action.
The $5.3-million Laboratory for Clinical Magnetoencephalography (MEG) recently opened at the IWK Health Centre in Halifax, in partnership with NRC and Helsinki-based Elekta Neuromag®, the manufacturer of the real-time MEG brain-mapping instrument.
Using advanced imaging technology, the MEG lab will measure brain activity – in both adults and children – as it is happening as opposed to just receiving a static image of the brain.

With MEG, the brain is seen in action rather than as a still image. The blue dot shows the location of activity in the auditory cortex of a person listening to basic auditory tones. Credit: www.cnrc-nrc.gc.ca
Read the entire article here : Observing the brain in space and time
Amanda Momberg of Cedarburg, Wis., was 8 years old when she fell to the kitchen floor and experienced her first epileptic seizure.
“I would shake on one side and I couldn’t talk,” she said. “But I would hear people talking to me.”
For most of her life, she took medication to control the seizures..But in December 2008, at age 16, the medications stopped working. Amanda suddenly started having 60 to 100 seizures a day.
“It was awful,” said Amanda’s mother, Kathy Momberg. “I was not in control; you couldn’t do anything about it.”
Doctors hoped surgery would help, but the surgeons’ first attempt to remove the part of her brain causing the seizures was not successful.
“That’s when the topic of MEG scan came up,” said Kathy Momberg.
Magnetoencophalography, or MEG, is an imaging technique used by doctors to detect changes in the brain. But unlike other imaging tests, the MEG scanner tracks changes in the brain instantaneously.
Because of Amanda’s nearly continuous seizures, Dr. Manoj Raghavan, a neurologist at Froedtert & Medical College in Milwaukee., suggested using MEG to see if there were more parts of Amanda’s brain tissue involved in the seizures they could remove without affecting vital parts of her brain.
The MEG scanner can detect changes in brain waves that occur on the order of milliseconds, as opposed to a second or more with magnetic resonance imaging (MRI). And for a select few patients like Amanda, those extra milliseconds can mean the difference between life and death.
When Froedtert & Medical College of Wisconsin received the MEG scanner, Amanda became their first patient.
To Read the Entire Story : http://abcnews.go.com/GMA/MindMoodNews/sixty-seizures-brain-scan-detects-source/story?id=9730383

